BACKGROUND Hepatic stellate cells (HSCs) play an important function in hepatic fibrogenesis. Our current scientific research indicated that the Zi Qi decoction, a Conventional Chinese language Drugs system, exhibited good efficacy in assuaging liver fibrosis, however the underlying mechanism stays elusive. MATERIAL AND METHODS Rats repeatedly injected with CCl₄ and cells stimulated with lipopolysaccharide had been used as in vivo and in vitro fashions for liver fibrosis, respectively.
The viability of LX-2 cells was evaluated with MTT assay. Relative messenger RNA (mRNA) expression of consultant extracellular matrix (ECM) parts was detected with real-time quantitative polymerase chain response (RT-qPCR). Furthermore, complete and phosphorylation ranges of ECM proteins and pathway-related proteins had been detected with western blotting. Immunofluorescent staining was used to point out the nuclear translocation of nuclear issue kappa b (NF-kappaB) p65.
Hematoxylin & eosin (H&E) and Masson trichrome staining and immunohistochemistry had been carried out to judge the extent of liver fibrosis. The degrees of alanine transaminase (ALT), aspartate transaminase (AST), gamma-glutamyl transpeptidase (GGT), Hyp, tumor necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6) had been examined with an enzyme-linked immunosorbent assay. As well as, 7.0T micro-magnetic resonance imaging (micro-MRI) was used to judge the severity of hepatic injury.
RESULTS The Zi Qi decoction inhibited lipopolysaccharide-mediated upregulation of mRNA and protein ranges of consultant ECM proteins each in vivo and in vitro. The Zi Qi decoction additionally suppressed activation of the Toll-like receptor 4 (TLR4)-related NF-kappaB signaling pathway and subsequently inhibited the nuclear translocation of activated NF-kappaB. Furthermore, one other TLR4 downstream pathway, mitogen-activated protein kinase (MAPK), was concurrently restrained. The outcomes of liver pathology and MRI in rat fashions additionally steered the efficacy of the Zi Qi decoction in attenuating liver injury. CONCLUSIONS The Zi Qi decoction inhibited liver fibrosis by inhibiting the TLR4-related NF-kB and MAPK signaling pathways and stopping activation of HSCs.
Kinase-mediated RAS signaling by way of membraneless cytoplasmic protein granules
Receptor tyrosine kinase (RTK)-mediated activation of downstream effector pathways such because the RAS GTPase/MAP kinase (MAPK) signaling cascade is assumed to happen completely from lipid membrane compartments in mammalian cells. Right here, we uncover a membraneless, protein granule-based subcellular construction that may manage RTK/RAS/MAPK signaling in most cancers. Chimeric (fusion) oncoproteins involving sure RTKs together with ALK and RET bear de novo higher-order meeting into membraneless cytoplasmic protein granules that actively sign.
These pathogenic biomolecular condensates regionally focus the RAS activating complicated GRB2/SOS1 and activate RAS in a lipid membrane-independent method. RTK protein granule formation is vital for oncogenic RAS/MAPK signaling output in these cells. We establish a set of protein granule parts and set up structural guidelines that outline the formation of membraneless protein granules by RTK oncoproteins. Our findings reveal membraneless, higher-order cytoplasmic protein meeting as a definite subcellular platform for organizing oncogenic RTK and RAS signaling.
CDC2-like (CLK) protein kinase inhibition as a novel focused therapeutic technique in prostate most cancers
Dysregulation of other splicing is a function of most cancers, each in aetiology and development. It happens due to mutations in splice websites or websites that regulate splicing, or due to the altered expression and exercise of splice elements and of splice issue kinases that regulate splice issue exercise. Not too long ago the CDC2-like kinases (CLKs) have attracted consideration on account of their growing involvement in most cancers. We measured the impact of the CLK inhibitor, the benzothiazole TG003, on two prostate most cancers cell strains. TG003 decreased cell proliferation and elevated apoptosis in PC3 and DU145 cells.
Conversely, the overexpression of CLK1 in PC3 cells prevented TG003 from decreasing cell proliferation. TG003 slowed scratch closure and decreased cell migration and invasion in a transwell assay. TG003 decisively inhibited the expansion of a PC3 cell line xenograft in nude mice. We carried out a transcriptomic evaluation of cells handled with TG003. We report widespread and constant adjustments in various splicing of cancer-associated genes together with CENPE, ESCO2, CKAP2, MELK, ASPH and CD164 in each HeLa and PC3 cells. Collectively these findings counsel that concentrating on CLKs will present novel therapeutic alternatives in prostate most cancers.
Protein kinase A controls the hexosamine pathway by tuning the suggestions inhibition of GFAT-1
The hexosamine pathway (HP) is a key anabolic pathway whose product uridine 5′-diphospho-N-acetyl-D-glucosamine (UDP-GlcNAc) is a vital precursor for glycosylation processes in mammals. It modulates the ER stress response and HP activation extends lifespan in Caenorhabditis elegans. The extremely conserved glutamine fructose-6-phosphate amidotransferase 1 (GFAT-1) is the rate-limiting HP enzyme. GFAT-1 exercise is modulated by UDP-GlcNAc suggestions inhibition and by way of phosphorylation by protein kinase A (PKA). Molecular penalties of GFAT-1 phosphorylation, nevertheless, stay poorly understood.
Right here, we establish the GFAT-1 R203H substitution that elevates UDP-GlcNAc ranges in C. elegans. In human GFAT-1, the R203H substitution interferes with UDP-GlcNAc inhibition and with PKA-mediated Ser205 phosphorylation. Our knowledge point out that phosphorylation impacts the interactions of the 2 GFAT-1 domains to regulate catalytic exercise. Notably, Ser205 phosphorylation has two discernible results: it lowers baseline GFAT-1 exercise and abolishes UDP-GlcNAc suggestions inhibition. PKA controls the HP by uncoupling the metabolic suggestions loop of GFAT-1.
Modifications in expression of lysosomal membrane proteins in leucocytes of most cancers sufferers handled with tyrosine kinase inhibitors
Lysosomal sequestration of weak base medication has been recognized as one of many stress-related mechanisms that set off in vitro lysosomal biogenesis managed by transcription issue EB (TFEB). Whether or not such mechanism can induce lysosomal biogenesis in vivo is unknown. On this research, we addressed the query whether or not extended remedy with sunitinib (SUN) in sufferers with superior renal cell carcinoma (n = 22) and with imatinib (IM) in these with gastrointestinal stromal tumor (n = 6) might induce lysosomal biogenesis in leukocytes.
Lysosomal biogenesis was monitored utilizing immunoblotting of three lysosomal membrane proteins: lysosome-associated membrane proteins 1 and a couple of (LAMP1 and LAMP2) and vacuolar H+-ATPase, B2 subunit (ATP6V1B2). Current outcomes point out that extended remedy with SUN impacts LAMP1 and LAMP2 expression solely marginally in most sufferers. In distinction, adjustments in ATP6V1B2 expression had been marked and resembled irregular oscillations.
Mouse Angiopoietin Like Protein 3 ELISA kit |
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| E03A0506-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Mouse Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Angiopoietin Like Protein 3 ELISA kit |
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| E03A0506-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Mouse Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Angiopoietin-like Protein 3, HEK Protein |
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| 20-abx263227 | Abbexa |
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Anti-Angiopoietin-like 4 Antibody |
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| STJ500081 | St John's Laboratory | 100 µg | EUR 476 |
Recombinant Angiopoietin Like Protein 3 (ANGPTL3) |
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| 4-RPB699Hu01 | Cloud-Clone |
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Description: Recombinant Human Angiopoietin Like Protein 3 expressed in: E.coli |
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Recombinant Angiopoietin Like Protein 3 (ANGPTL3) |
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| 4-RPB699Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Angiopoietin Like Protein 3 expressed in: E.coli |
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Recombinant Angiopoietin Like Protein 3 (ANGPTL3) |
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| 4-RPB699Mu02 | Cloud-Clone |
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Description: Recombinant Mouse Angiopoietin Like Protein 3 expressed in: E.coli |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx129753 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx121014 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx110976 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx103092 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx103093 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| abx036974-100ug | Abbexa | 100 ug | EUR 391 |
Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx137513 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx000824 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| abx032949-400ul | Abbexa | 400 ul | EUR 523 |
Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| abx032949-80l | Abbexa | 80 µl | EUR 286 |
Recombinant Human Angiopoietin-like Protein 3 |
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| 7-00061 | CHI Scientific | 2µg | Ask for price |
Recombinant Human Angiopoietin-like Protein 3 |
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| 7-00062 | CHI Scientific | 10µg | Ask for price |
Recombinant Human Angiopoietin-like Protein 3 |
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| 7-00063 | CHI Scientific | 1mg | Ask for price |
Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| abx432327-200ul | Abbexa | 200 ul | EUR 286 |
Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx175387 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx171223 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx171224 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| 20-abx301351 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody |
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| abx230398-100ug | Abbexa | 100 ug | EUR 509 |
Angiopoietin Like Protein 3 (ANGPTL3) Polyclonal Antibody (Mouse) |
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| 4-PAB699Mu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Angiopoietin Like Protein 3 (ANGPTL3) |
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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| SEB699Mu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 2957.81 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Angiopoietin Like Protein 3 (ANGPTL3) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| SEB699Mu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 331.23 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Angiopoietin Like Protein 3 (ANGPTL3) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| SEB699Mu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 430.33 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Angiopoietin Like Protein 3 (ANGPTL3) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| SEB699Mu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 1636.49 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Angiopoietin Like Protein 3 (ANGPTL3) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| 4-SEB699Mu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Angiopoietin Like Protein 3 (ANGPTL3) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species. |
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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| RD-ANGPTL3-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 356 |
Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| RD-ANGPTL3-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 488 |
Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| DLR-ANGPTL3-Mu-48T | DL Develop | 48T | EUR 371 |
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Description: A sandwich quantitative ELISA assay kit for detection of Mouse Angiopoietin Like Protein 3 (ANGPTL3) in samples from serum, plasma, tissue homogenates or other biological fluids. |
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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| DLR-ANGPTL3-Mu-96T | DL Develop | 96T | EUR 473 |
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Description: A sandwich quantitative ELISA assay kit for detection of Mouse Angiopoietin Like Protein 3 (ANGPTL3) in samples from serum, plasma, tissue homogenates or other biological fluids. |
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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| abx570757-96tests | Abbexa | 96 tests | EUR 637 |
Mouse Angiopoietin Like Protein 3 (ANGPTL3) CLIA Kit |
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| 20-abx493008 | Abbexa |
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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| abx518186-96tests | Abbexa | 96 tests | EUR 637 |
Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| 20-abx153640 | Abbexa |
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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| RDR-ANGPTL3-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 372 |
Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit |
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| RDR-ANGPTL3-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 510 |
Mouse Angiopoietin Like Protein 3(ANGPTL3)ELISA kit |
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| QY-E20091 | Qayee Biotechnology | 96T | EUR 361 |
Mouse Angiopoietin-like protein 8 (Angptl8) |
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| 1-CSB-YP844436MO | Cusabio |
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Description: Recombinant Mouse Angiopoietin-like protein 8(Angptl8) expressed in Yeast |
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Mouse Angiopoietin-like protein 8 (Angptl8) |
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| 1-CSB-EP844436MO | Cusabio |
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Description: Recombinant Mouse Angiopoietin-like protein 8(Angptl8) expressed in E.coli |
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Rat Angiopoietin Like Protein 3 (ANGPTL3) Protein |
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| 20-abx652513 | Abbexa |
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Human Angiopoietin Like Protein 3 (ANGPTL3) Protein |
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| 20-abx065334 | Abbexa |
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Rabbit Polyclonal antibody Anti-CRBN |
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| Anti-CRBN | ImmunoStep | 50 µg | EUR 349 |
Anti-Angiopoietin-like 4/ANGPTL4 Antibody |
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| PA1435 | BosterBio | 100ug/vial | EUR 294 |
Anti-Angiopoietin-like 4 Antibody BIOTIN |
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| STJ500082 | St John's Laboratory | 100 µg | EUR 586 |
Anti-Angiopoietin-like 4 Antibody FITC |
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| STJ500083 | St John's Laboratory | 100 µg | EUR 586 |
Anti-Angiopoietin-like 4?/ANGPTL4 Antibody |
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| A01147 | BosterBio | 100ug/vial | EUR 294 |
Anti-ANGPTL7/Angiopoietin Like 7 Antibody |
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| A11067 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal ANGPTL7/Angiopoietin Like 7 Antibody. Validated in WB and tested in Human. |
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Anti-Angptl7/Angiopoietin Like 7 Antibody |
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| A11067-1 | BosterBio | 100ul | EUR 397 |
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Description: Rabbit Polyclonal Antibody for Angptl7 Antibody (ANGPTL7) detection.tested for WB in Human, Mouse. |
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Mouse Angiopoietin Like Protein 1 (ANGPTL1) Protein |
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| 20-abx065326 | Abbexa |
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Mouse Angiopoietin Like Protein 2 (ANGPTL2) Protein |
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| 20-abx065332 | Abbexa |
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Mouse Angiopoietin Like Protein 4 (ANGPTL4) Protein |
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| 20-abx065337 | Abbexa |
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Mouse Angiopoietin Like Protein 6 (ANGPTL6) Protein |
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| 20-abx065341 | Abbexa |
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Mouse Angiopoietin Like Protein 7 (ANGPTL7) Protein |
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| 20-abx065342 | Abbexa |
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Mouse Angiopoietin Like Protein 8 (ANGPTL8) Protein |
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| 20-abx165988 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Polyclonal Antibody (Mouse), APC |
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| 4-PAB699Mu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Angiopoietin Like Protein 3 (ANGPTL3). This antibody is labeled with APC. |
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Angiopoietin Like Protein 3 (ANGPTL3) Polyclonal Antibody (Mouse), Biotinylated |
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| 4-PAB699Mu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Angiopoietin Like Protein 3 (ANGPTL3). This antibody is labeled with Biotin. |
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Angiopoietin Like Protein 3 (ANGPTL3) Polyclonal Antibody (Mouse), Cy3 |
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| 4-PAB699Mu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Angiopoietin Like Protein 3 (ANGPTL3). This antibody is labeled with Cy3. |
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Angiopoietin Like Protein 3 (ANGPTL3) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB699Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Angiopoietin Like Protein 3 (ANGPTL3). This antibody is labeled with FITC. |
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Angiopoietin Like Protein 3 (ANGPTL3) Polyclonal Antibody (Mouse), HRP |
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| 4-PAB699Mu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Angiopoietin Like Protein 3 (ANGPTL3). This antibody is labeled with HRP. |
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Angiopoietin Like Protein 3 (ANGPTL3) Polyclonal Antibody (Mouse), PE |
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| 4-PAB699Mu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Angiopoietin Like Protein 3 (ANGPTL3). This antibody is labeled with PE. |
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Angiopoietin Like Protein 3 (ANGPTL3) Polyclonal Antibody (Human, Mouse) |
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| 4-PAB699Mu02 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Mouse Angiopoietin Like Protein 3 (ANGPTL3) |
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ELISA kit for Mouse ANGPTL3 (Angiopoietin Like Protein 3) |
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| E-EL-M2458 | Elabscience Biotech | 1 plate of 96 wells | EUR 534 |
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Description: A sandwich ELISA kit for quantitative measurement of Mouse ANGPTL3 (Angiopoietin Like Protein 3) in samples from Serum, Plasma, Cell supernatant |
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ELISA kit for Mouse ANGPTL3 (Angiopoietin Like Protein 3) |
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| ELK1328 | ELK Biotech | 1 plate of 96 wells | EUR 372 |
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Description: A sandwich ELISA kit for detection of Angiopoietin Like Protein 3 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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Angiopoietin-like Protein 2 Protein |
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| 20-abx262409 | Abbexa |
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Angiopoietin-like Protein 6 Protein |
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| 20-abx262419 | Abbexa |
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Angiopoietin-like Protein 4 Protein |
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| 20-abx262981 | Abbexa |
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Recombinant Human ANGPTL3/Angiopoietin-like 3 Protein |
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| RP01024 | Abclonal | 5 μg | EUR 136 |
Angiopoietin Like Protein 3 (ANGPTL3) Antibody (HRP) |
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| 20-abx306363 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody (FITC) |
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| 20-abx306364 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody (Biotin) |
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| 20-abx306365 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody Pair |
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| 20-abx370495 | Abbexa |
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Angiopoietin Like Protein 3 (ANGPTL3) Antibody Pair |
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| 20-abx370536 | Abbexa |
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Human Angiopoietin Like Protein 3 ELISA kit |
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| E01A0506-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Human Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Angiopoietin Like Protein 3 ELISA kit |
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| E01A0506-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Human Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Angiopoietin Like Protein 3 ELISA kit |
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| E01A0506-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Human Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Angiopoietin Like Protein 3 ELISA kit |
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| E04A0506-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Rabbit Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Angiopoietin Like Protein 3 ELISA kit |
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| E04A0506-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Rabbit Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Angiopoietin Like Protein 3 ELISA kit |
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| E04A0506-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Rabbit Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Angiopoietin Like Protein 3 ELISA kit |
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| E02A0506-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Rat Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Angiopoietin Like Protein 3 ELISA kit |
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| E02A0506-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Rat Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Angiopoietin Like Protein 3 ELISA kit |
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| E02A0506-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Rat Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Angiopoietin Like Protein 3 ELISA kit |
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| E06A0506-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Goat Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Angiopoietin Like Protein 3 ELISA kit |
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| E06A0506-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Goat Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Angiopoietin Like Protein 3 ELISA kit |
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| E06A0506-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Goat Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Angiopoietin Like Protein 3 ELISA kit |
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| E07A0506-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Porcine Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Angiopoietin Like Protein 3 ELISA kit |
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| E07A0506-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Porcine Angiopoietin Like Protein 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Very comparable adjustments within the expression of lysosomal membrane proteins had been additionally present in IM-treated sufferers. Conclusion: extended remedy of most cancers sufferers with SUN and IM didn’t induce leucocyte lysosomal biogenesis however dramatically affected expression of ATP6V1B2.