The p70 ribosomal S6 kinase (S6K) household is a bunch of extremely conserved kinases in eukaryotes that regulates cell development, cell proliferation, and stress response by way of modulating protein synthesis and ribosomal biogenesis. S6Ks are downstream effectors of the Goal of Rapamycin (TOR) pathway, which connects nutrient and power signaling to development and homeostasis, below regular and stress circumstances.
The plant S6K household consists of two isoforms, S6K1 and S6K2, which, regardless of their excessive degree of sequence similarity, have distinct features and regulation mechanisms. Important advances on the characterization of human S6Ks have occurred up to now few years, whereas research on plant S6Ks are scarce. On this article, we evaluation expression and activation of the 2 S6K isoforms in vegetation and we talk about their roles in mediating responses to stresses and developmental cues.
Interplay of Trypanosoma cruzi Gp82 With Host Cell LAMP2 Induces Protein Kinase C Activation and Promotes Invasion
The floor molecule gp82 of metacyclic trypomastigote (MT) types of Trypanosoma cruzi, the protozoan parasite that causes Chagas illness, mediates the host cell invasion, a course of crucial for the institution of an infection. Gp82 is thought to bind to the goal cell in a receptor-dependent method, triggering Ca2+ sign, actin cytoskeleton rearrangement and lysosome spreading.
The host cell receptor for gp82 was not too long ago recognized as LAMP2, the most important lysosome membrane-associated protein. To additional make clear the mechanisms of MT invasion, we aimed on this research at figuring out the LAMP2 area that interacts with gp82 and investigated whether or not goal cell PKC and ERK1/2, beforehand advised to be implicated in MT invasion, are activated by gp82. Interplay of MT, or the recombinant gp82 (r-gp82), with human epithelial HeLa cells induced the activation of Ca2+-dependent PKC and ERK1/2. The LAMP2 sequence predicted to bind gp82 was mapped and the artificial peptide primarily based on that sequence inhibited MT invasion, impaired the binding of r-gp82 to HeLa cells, and blocked the PKC and ERK1/2 activation induced by r-gp82.
Therapy of HeLa cells with particular inhibitor of focal adhesion kinase resulted in inhibition of r-gp82-induced PKC and ERK1/2 activation, in addition to in alteration of the actin cytoskeleton structure. PKC activation by r-gp82 was additionally impaired by therapy of HeLa cells with inhibitor of phospholipase C, which mediates the manufacturing of diacylglycerol, which prompts PKC, and inositol 1,4,5-triphosphate that releases Ca2+ from intracellular shops.
Taken collectively, our outcomes point out that recognition of MT gp82 by LAMP2 induces within the host cell the activation of phosholipase C, with technology of merchandise that contribute for PKC activation and the downstream ERK1/2. This chain of occasions results in the actin cytoskeleton disruption and lysosome spreading, selling MT internalization.
GLP-1 reduces the migration of hepatocellular carcinoma cells by way of suppression of the stress-activated protein kinase/c-Jun N-terminal kinase pathway
Incretins, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are hormones secreted from small gut accompanied with oral consumption. We beforehand confirmed that reworking development issue (TGF)-α stimulates the migration of hepatocellular carcinoma (HCC) cells by way of mitogen-activated protein (MAP) kinases, AKT and Rho-kinase. Nevertheless, it stays to be elucidated whether or not incretins have an effect on HCC cell features.
Within the current research, due to this fact, we investigated whether or not incretins have an effect on the migration of HCC cells utilizing human HCC-derived HuH7 cells. GLP-1, however not GIP, diminished each TGF-α- and hepatocyte development issue (HGF)-induced cell migration. IBMX, an inhibitor of cyclic nucleotide phosphodiesterase, enhanced the suppressive impact of GLP-1. GLP-1 attenuated the phosphorylation of stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) by TGF-α and HGF. Our outcomes strongly recommend that GLP-1 suppresses TGF-α- and HGF-induced migration of HCC cells by inhibiting the SAPK/JNK signaling pathway, and that the inhibition by GLP-1 is because of cAMP manufacturing.
Spinocerebellar Ataxia Sort 1 protein Ataxin-1 is signalled to DNA injury by Ataxia Telangiectasia Mutated kinase
Spinocerebellar Ataxia Sort 1 (SCA1) is an autosomal dominant neurodegenerative dysfunction brought on by a polyglutamine enlargement within the ataxin-1 protein. Latest genetic correlational research have implicated DNA injury restore pathways in modifying the age at onset of illness signs in SCA1 and Huntington’s Illness, one other polyglutamine enlargement illness. We exhibit that each endogenous and transfected ataxin-1 localizes to websites of DNA injury, which is impaired by polyglutamine enlargement. This response depends on ataxia telangiectasia mutated (ATM) kinase exercise.
Additional, we characterize an ATM phosphorylation motif inside ataxin-1 at serine 188. We present discount of the Drosophila ATM homolog ranges in a ATXN1[82Q] Drosophila mannequin by shRNA or genetic cross ameliorates motor signs. These findings supply a attainable clarification as to why DNA restore was implicated in SCA1 pathogenesis by previous research. The similarities between the ataxin-1 and the huntingtin responses to DNA injury present additional help for a shared pathogenic mechanism for polyglutamine enlargement illnesses.
Arabidopsis cysteine-rich receptor-like protein kinase CRK33 impacts stomatal density and drought tolerance
Cysteine-rich receptor-like protein kinases (CRKs) are transmembrane proteins containing two domains of unknown operate 26 (DUF26) RLKs of their ectodomain. Regardless of that CRKs management necessary facets of plant improvement, solely few proteins have functionally been characterised. On this work, we analyzed the operate of CRK33 by characterizing two insertional traces.
The stomatal density and stomatal index have been decreased in crk33-2 and crk33-3 vegetation compared to wild-type vegetation, correlating with a decreased transpiration in transgenic vegetation and the next drought tolerance. Moreover, photosynthesis and stomatal conductance modified.
 R - Jagged -1(188 - 206), Notch Ligand) R-JAG (188 - 206) R - Jagged -1(188 - 206), Notch Ligand |
|
5-01864 |
CHI Scientific |
4 x 1mg |
Ask for price |
 SARS-CoV-2 Nucleocapsid Protein, Avi-His-tag |
|
E80027 |
EpiGentek |
|
|
, Jagged - 1 (188 - 204), Notch Ligand (AA: Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Cys-Arg-Pro-Arg) (MW: 2107.37)) JAG - 1 (188 - 204), Jagged - 1 (188 - 204), Notch Ligand (AA: Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Cys-Arg-Pro-Arg) (MW: 2107.37) |
|
SP-56614-1 |
Alpha Diagnostics |
1 mg |
EUR 196.8 |
 SARS-CoV-2 Spike S1 RBD Protein, Avi-His-tag |
|
E80024 |
EpiGentek |
|
|
 SARS-CoV-2 Spike S1 RBD Protein, Mouse Fc-fusion |
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E80026 |
EpiGentek |
|
|
 Protein, Avi-His-tag) SARS-CoV-2 Spike S1 (16-685) Protein, Avi-His-tag |
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E80021 |
EpiGentek |
|
|
 Protein, Avi-His-tag) SARS-CoV-2 Spike S1 RBD (V367F) Protein, Avi-His-tag |
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E80023 |
EpiGentek |
|
|
 Protein, Fc Fusion, Avi-tag) SARS-CoV-2 Spike S1 (13-665) Protein, Fc Fusion, Avi-tag |
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E80020 |
EpiGentek |
|
|
 Protein, Fc Fusion, Avi-tag) SARS-CoV-2 Spike S1 (16-685) Protein, Fc Fusion, Avi-tag |
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E80022 |
EpiGentek |
|
|
 SARS-CoV-2 Spike S1 RBD Protein, Human Fc-Fusion, Avi-Tag |
|
E80025 |
EpiGentek |
|
|
 Histone H3 Methylation Antibody Panel Pack I – Active Genes |
|
C10000 |
EpiGentek |
|
|
 Histone H3 Methylation Antibody Panel Pack I – Repression Genes |
|
C10001 |
EpiGentek |
|
|
 Histone H3 Methylation Antibody Panel Pack II – Active Genes |
|
C10002 |
EpiGentek |
|
|
 Histone H3 Methylation Antibody Panel Pack II – Repression Genes |
|
C10003 |
EpiGentek |
|
|
 Histone H3 Methylation Antibody Panel Pack III – Active Genes |
|
C10004 |
EpiGentek |
|
|
 Histone H3K4 Methylation Antibody Panel Pack |
|
C10005 |
EpiGentek |
|
|
 Histone H3K9 Methylation Antibody Panel Pack |
|
C10006 |
EpiGentek |
|
|
 Histone H3K27 Methylation Antibody Panel Pack |
|
C10007 |
EpiGentek |
|
|
 Histone H3K36 Methylation Antibody Panel Pack |
|
C10008 |
EpiGentek |
|
|
 Histone H3K79 Methylation Antibody Panel Pack |
|
C10009 |
EpiGentek |
|
|
 Histone H3 Acetylation Antibody Panel Pack I |
|
C10010 |
EpiGentek |
|
|
 Histone H3 Acetylation Antibody Panel Pack II |
|
C10011 |
EpiGentek |
|
|
 Histone H4K20 Methylation Antibody Panel Pack |
|
C10012 |
EpiGentek |
|
|
 Histone H4 Acetylation Antibody Panel Pack |
|
C10013 |
EpiGentek |
|
|
 Histone H3 Phosphorylation Antibody Panel Pack |
|
C10014 |
EpiGentek |
|
|
 Histone H3R2 Methylation Antibody Panel Pack |
|
C10015 |
EpiGentek |
|
|
 Histone H3R8 Methylation Antibody Panel Pack |
|
C10016 |
EpiGentek |
|
|
 Histone H3R17 Methylation Antibody Panel Pack |
|
C10017 |
EpiGentek |
|
|
 Histone H3R26 Methylation Antibody Panel Pack |
|
C10018 |
EpiGentek |
|
|
 Histone H4R3 Methylation Antibody Panel Pack |
|
C10019 |
EpiGentek |
|
|
 DNA Methylation Antibody Panel Pack I |
|
C20000 |
EpiGentek |
|
|
 Goat Anti-Rabbit Secondary Antibody, Biotin Conjugated |
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A12001 |
EpiGentek |
|
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 Goat Anti-Rat Secondary Antibody, Biotin Conjugated |
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A12002 |
EpiGentek |
|
|
 HRP-Goat Anti-Mouse Secondary Antibody |
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A12003 |
EpiGentek |
|
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 HRP-Goat Anti-Rabbit Secondary Antibody |
|
A12004 |
EpiGentek |
|
|
 Magnetic Separator) EpiMag HT (96-Well) Magnetic Separator |
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Q10002 |
EpiGentek |
|
|
 ) EpiMag 96-Well Microplate (5/pack) |
|
Q10003 |
EpiGentek |
|
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 Recombinant TMPRSS2 Protein, Partial |
|
E80017 |
EpiGentek |
-
EUR 423.50
-
EUR 660.00
-
EUR 2321.00
|
|
 Recombinant Transmembrane Protease Serine 2 Protein, Partial |
|
E80016 |
EpiGentek |
-
EUR 470.80
-
EUR 753.50
-
EUR 1824.90
|
|
 R - Jagged - 1(188 - 206), Notch Ligand (AA: Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Gly-Arg-Pro-Arg-Asp-Asp) (MW: 2291.46)) R-JAG (188 - 206) R - Jagged - 1(188 - 206), Notch Ligand (AA: Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Gly-Arg-Pro-Arg-Asp-Asp) (MW: 2291.46) |
|
SP-86688-1 |
Alpha Diagnostics |
1 mg |
EUR 196.8 |
 (D614G), Partial) Recombinant SARS-CoV-2 Spike Glycoprotein(S) (D614G), Partial |
|
E80028 |
EpiGentek |
|
|
) MCP-1 Monocyte Chemotactic Protein-1 Mouse Recombinant Protein (CCL2) |
|
PROTP10148-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: Monocyte Chemotactic Protein-1 Mouse Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 125 amino acids and having a molecular mass of 14 kDa. ;The MCP-1 is purified by proprietary chromatographic techniques. |
) MCP-1 Monocyte Chemotactic Protein-1 Human Recombinant Protein (CCL2) |
|
PROTP13500-1 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
|
Description: Monocyte Chemotactic Protein-1 Human Recombinant also known as Monocyte Chemotactic and Activating Factor (MCAF) produced in E.Coli is a non-glycosylated, Polypeptide chain containing 76 amino acids and having a molecular mass of 8.6kDa. ;The MCP-1 is purified by proprietary chromatographic techniques. |
) Amyloid ?-Protein (1-15) |
|
A1003-1 |
ApexBio |
1 mg |
EUR 135.6 |
|
Description: Beta-amyloid protein (A beta), a 39-43 amino acid peptide composed of a portion of the transmembrane domain and the extracellular domain of the amyloid precursor protein (APP), is also the principal component of amyloid. |
, human recombinant protein) Neuregulin/Heregulin-1? (NRG-1?/HRG-1?), human recombinant protein |
|
P1054-1 |
ApexBio |
1 mg |
EUR 4736.4 |
|
Description: Neuregulin (NRG) is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells and plays an important role in heart structure and function through inducing cardiomyocyte differentiation |
 IL-1-beta Interleukin-1 betaHuman Recombinant Protein |
|
PROTP01584-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: Interleukin-1 beta Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.;The IL-1b is purified by proprietary chromatographic techniques. |
 MMP-1 Matrix Metalloproteinase-1 Human Recombinant Protein |
|
PROTP03956-1 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
|
Description: MMP 1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 393 amino acids (100-469a.a) and having a molecular mass of 45kDa. MMP 1 is fused to a 23 amino acid His-tag at N-terminus. |
 Methylamp 96 DNA Modification Kit |
|
P-1008 |
EpiGentek |
|
|
 ) Nucleic Acid Isolation Enhancer (Glycogen Solution) |
|
R-1001 |
EpiGentek |
|
|
 Methylamp PCR Enhancer |
|
R-1002 |
EpiGentek |
|
- 400 Reactions
- 400 Reactions
|
 ) Streptavidin-Coated Strip Microwell Plate (Flat) |
|
R-1102 |
EpiGentek |
|
|
 DTT Solution |
|
R-1104 |
EpiGentek |
|
- 1 ml, 500 mM
- 1 ml, 500 mM
|
 EpiQuik Nuclear Extraction Kit |
|
OP-0002 |
EpiGentek |
|
- 100 Assays
- 100 Extractions
|
 HIV-1 Tat Protein Peptide |
|
B1433-1 |
ApexBio |
1 mg |
EUR 153.6 |
|
Description: HIV-1 Tat Protein Peptide |
 ApoA-1, human recombinant protein |
|
P1052-.1 |
ApexBio |
100 µg |
EUR 375.6 |
|
Description: Apolipoprotein A-1 (ApoA-1) is a glycoprotein produced in the liver and intestine that is the major protein component of high density lipoprotein (HDL) particles. ApoA-1 is involved in the reverse transport of cholesterol from peripheral tissues to the liver for recycling and excretion. |
ApoA-1, human recombinant protein |
|
P1052-1 |
ApexBio |
1 mg |
EUR 1863.6 |
|
Description: Apolipoprotein A-1 (ApoA-1) is a glycoprotein produced in the liver and intestine that is the major protein component of high density lipoprotein (HDL) particles. ApoA-1 is involved in the reverse transport of cholesterol from peripheral tissues to the liver for recycling and excretion. |
 WNT-1, human recombinant protein |
|
P1068-1 |
ApexBio |
1 mg |
EUR 8328 |
|
Description: The WNT gene family compose of structurally related genes that encode secreted signaling proteins. These proteins have been involved in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. |
 Recombinant Human ANG-1 Protein |
|
PROTQ15389-1 |
BosterBio |
20ug |
EUR 380.4 |
|
Description: Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a tyrosine-kinase receptor expressed primarily on vascular endothelial cells and early hematopoietic cells. Ang-1/ Tie-2 signaling promotes angiogenesis during the development, remodeling, and repair of the vascular system. Transgenic mice lacking expression of either Ang-1 or Tie-2 fail to develop a fully functional cardiovascular system and die before birth. Postnatally, the angiogenic activity of Ang-1/Tie-2 is required during normal tissue repair and remodeling of the female endometrium in the menstrual cycle. Ang-1/Tie-2 signaling appears to be regulated by Angiopoietin-2 (Ang-2), a natural antagonist for Tie-2 that exerts its effects through an internal autocrine loop mechanism. In addition to suppressing endothelial cell activation by inhibiting the expression of adhesion and inflammatory molecules, Ang-1 enhances endothelial cell survival and capillary morphogenesis, and lessens capillary permeability. As such, Ang-1 has a potential to become an effective therapeutic agent for treating various endothelium disorders, including several severe human pulmonary diseases. The efficacy of cell-based Ang-1 gene therapy for acute lung injury (ALI) has recently been studied in a rat model of ALI (1). The results of this study show that such therapy can markedly improve lung condition and suggest that Ang-1 therapy may represent a potential new strategy for the treatment and/or prevention of acute respiratory distress injury (ARDI), a significant cause of morbidity and mortality in critically ill patients. Recombinant human ANG-1, derived from HeLa cells, is a C-terminal histidine tagged glycoprotein which migrates with an apparent molecular mass of 60.0 – 70.0 kDa by SDS-PAGE under reducing conditions. Sequencing analysis shows N-terminal sequences starting with Ser-20 and with Asp-70 of the 498 amino acid precursor protein. |
 Recombinant Murine Cardiotrophin-1 Protein |
|
PROTQ60753-1 |
BosterBio |
10ug |
EUR 380.4 |
|
Description: CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NNT-1/BCSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Recombinant murine Cardiotrophin-1 is a 21.3 kDa protein consisting of 202 amino acid residues. |
 Recombinant Human Galectin-1 Protein |
|
PROTP09382-1 |
BosterBio |
50ug |
EUR 380.4 |
|
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues. |
 Recombinant Human PECAM-1 Protein |
|
PROTP16284-1 |
BosterBio |
50ug |
EUR 380.4 |
|
Description: PECAM is transmembrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. It is highly expressed at endothelial cell junctions, and also expressed in platelets and in most leukocyte sub-types. The primary function of PECAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. PECAM-1 has been implicated in the pathogenesis of various inflammation related disorders, including thrombosis, multiple sclerosis (MS), and rheumatoid arthritis. The human PECAM-1 gene codes for a 738 amino acid transmembrane glycoprotein containing a 118 amino acid cytoplasmic domain, a 19 amino acid transmembrane domain, and a 574 amino acid extracellular domain. Recombinant human PECAM-1 is a 572 amino acid glycoprotein comprising the extracellular domain of PECAM-1. Monomeric glycosylated PECAM-1 migrates at an apparent molecular weight of approximately 80.0-95.0 kDa by SDS-PAGE analysis under reducing conditions |
 Recombinant Human Gremlin-1 Protein |
|
PROTO60565-1 |
BosterBio |
50ug |
EUR 380.4 |
|
Description: Gremlin-1 (isoform-1) belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Gremlin is highly expressed in the small intestine, fetal brain, and colon and lower expression in brain, prostate, pancreas and skeletal muscle. Gremlin-1 regulates multiple functions in early development by specifically binding to and inhibiting the function of BMP-2, -4, and -7. It also plays a role in carcinogenesis and kidney branching morphogenesis. Recombinant Gremlin-1 is a 18.3 kDa protein containing 160 amino acid residues. |
 ORM1 Orosomucoid 1 Human protein |
|
PROTP02763-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: The Human Orosomucoid 1 produced from Human pooled serum has a molecular mass of 21.56kDa (calculated without glycosylation) containing 183 amino acid residues. |
 Canine IGF-1 Recombinant Protein |
|
R00148-1 |
BosterBio |
5ug/vial |
EUR 310.8 |
|
Description: Insulin-like growth factor 1 (IGF-1) is a primary mediator of the effects of growth hormone (GH) and has growth-promoting effects on almost every cell in the body. IGF-1 can also regulate cell growth and development, especially in nerve cells, as well as cellular DNA synthesis. Canine IGF-1 Recombinant Protein is purified insulin-like growth factor 1 (IGF-1) produced in yeast. |
 RAD51D (1-328 a.a.) Human Recombinant Protein) (1-328) RAD51D (1-328 a.a.) Human Recombinant Protein |
|
PROTO75771-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: RAD51D (1-328) Human Recombinant produced in E. coli is. a single polypeptide chain containing 351 amino acids and having a molecular mass of 37.4kDa. RAD51D (1-328) is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 VSNL1 Visinin-Like Protein-1 Human Recombinant Protein |
|
PROTP62760-1 |
BosterBio |
Regular: 50ug |
EUR 380.4 |
|
Description: VSNL1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 191 amino acids (1-191 a.a.) and having a molecular mass of 22.1kDa.;The VSNL1 is purified by proprietary chromatographic techniques. |
 DKK1 Dickkopf-Related Protein 1 Human Recombinant Protein |
|
PROTO94907-1 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
|
Description: DKK1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 258 amino acids (32-266 a.a) and having a molecular mass of 28.2kDa.;DKK1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 AssayMax ELISA Kit) Human KRAB-associated Protein 1 (KAP-1) AssayMax ELISA Kit |
|
EK2802-1 |
AssayPro |
96 Well Plate |
EUR 572.4 |
 GAD1 iso1 Glutamate Decarboxylase 1 Isoform-1 Human Recombinant Protein |
|
PROTQ99259-1 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
|
Description: GAD1 iso1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 617 amino acids (1-594 a.a) and having a molecular mass of 69.3kDa. GAD1 iso1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 Envelope-1, Dengue Virus Subtype 1 Recombinant Protein, Insect Cells |
|
PROTB1PNJ5-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: Recombinant Dengue Virus Subtype 1 produced in Insect Cells is a polypeptide chain containing amino acids 281-675 and having a molecular weight of approximately 50kDa. ;Dengue Envelope-1 is purified by proprietary chromatographic technique. |
 TGF-b-1 Transforming Growth Factor-beta 1 Human protein |
|
PROTP01137-1 |
BosterBio |
Regular: 2.5ug |
EUR 1388.4 |
|
Description: Human Transforming Growth Factor-beta 1 purified from Human Platelets having a molecular mass of 25kDa.;The TGF-b 1 is purified by proprietary chromatographic techniques. |
 Atholate™, protein hydrolysate, 1 kg |
|
0134-1 |
AthenaES |
1 kg |
EUR 332.4 |
, murine recombinant protein) JE (MCP-1), murine recombinant protein |
|
P1034-1 |
ApexBio |
1 mg |
EUR 4653.6 |
|
Description: JE (MCP-1), also known as chemokine (C-C motif) ligand 2 (CCL2), is a member of the CC chemokine family that is a chemotactic agent for mononuclear cells. |
 IFN-alpha 1, human recombinant protein |
|
P1058-.1 |
ApexBio |
100 µg |
EUR 375.6 |
|
Description: IFN-?1 (also called IFN-?) is a lymphoid factor with potent antiviral antiproliferative and immunomodulatory properties. Human IFN-?1 is a 19.3 kDa protein containing 166 amino acid residues. |
IFN-alpha 1, human recombinant protein |
|
P1058-1 |
ApexBio |
1 mg |
EUR 2732.4 |
|
Description: IFN-?1 (also called IFN-?) is a lymphoid factor with potent antiviral antiproliferative and immunomodulatory properties. Human IFN-?1 is a 19.3 kDa protein containing 166 amino acid residues. |
 CTF1 Cardiotrophin-1 Human Recombinant Protein |
|
PROTQ16619-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: Cardiotrophin-1 Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 201 amino acids and having a molecular mass of 21.2kDa.;The CTF1 is purified by proprietary chromatographic techniques. |
 Recombinant Rat IL-1 Beta Protein |
|
PROTQ63264-1 |
BosterBio |
10ug |
EUR 380.4 |
|
Description: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1β is a 17.4 kDa protein containing 153 amino acid residues. |
 Norovirus Group-1 Capsid Recombinant Protein |
|
PROTQ83884-1 |
BosterBio |
Regular: 0.5mg |
EUR 945.6 |
|
Description: The Recombinant Norovirus Group-1 Capsid, E.Coli derived, is a positive sense RNA virus with 7.5kb nucleotides, encoding a major structural protein VP1 with 58~60kDa and a VP2 protein. The full length of VP1 capsid protein is derived from the group 1 Norwalk virus. The protein is fused to a 6 His tag at N-terminal and purified by chromatography techniques. |
 NNT1 Neurotrophin-1 Human Recombinant Protein |
|
PROTQ9UBD9-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: Neurotrophin-1 Human Recombinant (28-225) produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 199 amino acids and having a molecular mass of 22kDa.;The NNT-1 is purified by proprietary chromatographic techniques. |
 HPSE Heparanase-1 Human Recombinant Protein |
|
PROTQ9Y251-1 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
|
Description: HPSE Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 531 amino acids (36-543 a.a) and having a molecular mass of 60kDa.;HPSE is fused to a 23 amino acid His-tag at N-terminus. |
 Protein) Recombinant Human LAG-1 (CCL4L1) Protein |
|
PROTP13236-1 |
BosterBio |
20ug |
EUR 380.4 |
|
Description: LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1β (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues. |
 Protein) Recombinant Rat MCP-1 (CCL2) Protein |
|
PROTP14844-1 |
BosterBio |
10ug |
EUR 380.4 |
|
Description: The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant rat MCP-1 is a 14.0 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. |
 SDC1 Syndecan-1 Human Recombinant Protein |
|
PROTP18827-1 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
|
Description: SDC1 Human Recombinant produced in E. coli is a single polypeptide chain containing 262 amino acids (18-254) and having a molecular mass of 27kDa (molecular size on SDS-PAGE will appear higher).;SDC1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 Recombinant Human Heregulin Beta -1 Protein |
|
PROTQ02297-1 |
BosterBio |
50ug |
EUR 380.4 |
|
Description: Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extracellular domain of the transmembrane NRG1 isoforms release soluble growth factors. HRG1-β1 contains an Ig domain and an EGF-like domain that is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. This binding induces erb3 and erb4 heterodimerization with erb2, stimulating intrinsic kinase activity, which leads to tyrosine phosphorylation. Although HRG1-β1 biological effects is still unclear, it has been found to promote motility and invasiveness of breast cancer cells which may also involve up-regulation of expression and function of the autocrine motility-promoting factor (AMF). Recombinant human Heregulin-β1 (HRG1-β1) is a 7.5 kDa polypeptide consisting of only the EGF domain of Heregulin-β1 (65 amino acid residues). |
 Recombinant Human sTRAIL Receptor-1 Protein |
|
PROTO00220-1 |
BosterBio |
50ug |
EUR 380.4 |
|
Description: TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain, " which can activate the cell's apoptotic machinery. These receptors are activated by binding to either membrane anchored or soluble TRAIL/Apo2L. Recombinant human soluble TRAIL Receptor-1/DR4 is a 22.7 kDa protein (215 amino acid residues) consisting of the TNFR homologous, cysteine rich portion of the extracellular domain. |
 Canine IL-1 beta Recombinant Protein |
|
R00101-1 |
BosterBio |
5ug/vial |
EUR 310.8 |
|
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Canine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast. |
 Canine IL-1 alpha Recombinant Protein |
|
R01144-1 |
BosterBio |
5ug/vial |
EUR 310.8 |
|
Description: IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Canine IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast. |
 Equine IFN beta 1 Recombinant Protein |
|
R02041-1 |
BosterBio |
5ug/vial |
EUR 310.8 |
|
Description: IFN beta is a mammalian Type I inferferon, functionig as a regulator of cellular activity by interacting with cell-surface receptors and activating various signaling pathways. IFN beta produces antiviral, antibacterial, and anticancer properties. Equine IFN beta Recombinant Protein is purified IFN beta produced in yeast. |
 FABP1 Fatty Acid Binding Protein-1 Human Recombinant Protein |
|
PROTP07148-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: FABP1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 127 amino acids and having a total molecular mass of 14.2kDa (calculated). |
 MAPK1 Mitogen-Activated Protein Kinase 1 Human Recombinant Protein |
|
PROTP28482-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: MAPK1 Recombinant (extracellular signal-regulated kinase) a Mitogen-Activated Protein Kinase, is a highly active form produced by phosphorylation of the purified ERK2/MAPK1 in vitro with MEK1 is a non-glycosylated polypeptide having a molecular mass of 44.6 kDa. _x000D_ MAPK1 is purified by proprietary chromatographic techniques._x000D_ |
 AssayMax ELISA kit) Human Heat Shock Factor Protein 1 (HSF 1) AssayMax ELISA kit |
|
EH5215-1 |
AssayPro |
96 Well Plate |
EUR 500.4 |
 Dynactin 2 (1-406 a.a.) Human Recombinant Protein) DCTN2 (1-406) Dynactin 2 (1-406 a.a.) Human Recombinant Protein |
|
PROTQ13561-1 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
|
Description: Dynactin 2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 429 amino acids (1-406 a.a) and having a molecular mass of 47.2kDa.;DCTN2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 Syntaxin-1A (1-265 a.a) Human Recombinant Protein) STX1A (1-265) Syntaxin-1A (1-265 a.a) Human Recombinant Protein |
|
PROTQ16623-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: STX1A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 265 amino acids (1-265 a.a) and having a molecular mass of 30.7kDa. |
 IL-1-beta Interleukin-1 beta Mouse Recombinant Protein, His Tag |
|
PROTP10749-1 |
BosterBio |
Regular: 25ug |
EUR 380.4 |
|
Description: Interleukin-1 beta Mouse Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 189 amino acids and having a molecular mass of 21 kDa. ;The IL-1b is fused to His-Tag and purified by proprietary chromatographic techniques. |
 IL-1-alpha Interleukin-1 alpha Rat Recombinant Protein, His Tag |
|
PROTP16598-1 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
|
Description: IL 1 alpha Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.2kDa. |
 Synaptobrevin-2 (1-94 a.a) Human Recombinant Protein) VAMP2 (1-94) Synaptobrevin-2 (1-94 a.a) Human Recombinant Protein |
|
PROTP63027-1 |
BosterBio |
Regular: 5ug |
EUR 380.4 |
|
Description: VAMP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 118 amino acids (1-94 a.a) and having a molecular mass of 12.8kDa.;VAMP2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 IL1RL1 Human, Interleukin-1 Receptor Like-1 Human Recombinant Protein, Sf9 |
|
PROTQ01638-1 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
|
Description: IL 1RL1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (19-328 a.a.) and fused to an 8 aa His Tag at C-terminus containing a total of 318 amino acids and having a molecular mass of 36.0kDa.;IL 1RL1 shows multiple bands between 40-57kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques. |
 Human Recombinant Protein) GLP-1 Glucagon Like Peptide-1 (31 a.a.) Human Recombinant Protein |
|
PROTP01275-1 |
BosterBio |
Regular: 50ug |
EUR 380.4 |
|
Description: Glucagon Like Peptide-1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 31 amino acids and having a molecular mass of 3298.7 Dalton. The GLP-1 is purified by proprietary chromatographic techniques. |
Lastly, all 4 stomata cell destiny genes have been upregulated, particularly the expression of TMM and SPCH within the mutant background, suggesting a job for CRK33 in stomatal spacing.